Ibrahim Aly and Rabab Zalat and Bahaa EL Deen W. El Aswad and Ismail M. Moharm and Basam M. Masoud and Tarek Diab
Novel Nanomagnetic Beads Based Latex Agglutination Assay for Rapid Diagnosis of Human Schistosomiasis Haematobium
977 - 983
2013
7
12
International Journal of Medical and Health Sciences
https://publications.waset.org/pdf/9997052
https://publications.waset.org/vol/84
World Academy of Science, Engineering and Technology
The objective of the present study was to evaluate the novel nanomagnetic beads based–latex agglutination assay (NMBLAT) as a simple test for diagnosis of S. haematobium as well as standardize the novel nanomagnetic beads based –ELISA (NMBELISA). According to urine examination this study included 85 S. haematobium infected patients, 30 other parasites infected patients and 25 negative control samples. The sensitivity of novel NMBLAT was 82.4 versus 96.5 and 88.2 for NMBELISA and currently used sandwich ELISA respectively. The specificity of NMBLAT was 83.6 versus 96.3 and 87.3 for NMBELISA and currently used sandwich ELISA respectively. In conclusion, the novel NMBELISA is a valuable applicable diagnostic technique for diagnosis of human schistosomiasis haematobium. The novel NMBELISA assay is a suitable applicable diagnostic method in field survey especially when followed by ELISA as a confirmatory test in query false negative results. Trials are required to increase the sensitivity and specificity of NMBELISA assay.
Open Science Index 84, 2013