%0 Journal Article
	%A Yuhei Kunihiro and  Sorin V. Sabau and  Kazuhiro Shibuya
	%D 2013
	%J International Journal of Bioengineering and Life Sciences
	%B World Academy of Science, Engineering and Technology
	%I Open Science Index 84, 2013
	%T A Geometrical Perspective on the Insulin Evolution
	%U https://publications.waset.org/pdf/9996884
	%V 84
	%X We study the molecular evolution of insulin from metric geometry point of view. In mathematics, and in particular in geometry, distances and metrics between objects are of fundamental importance.
Using a weaker notion than the classical distance, namely the weighted quasi-metrics, one can study the geometry of biological
sequences (DNA, mRNA, or proteins) space.
We analyze from geometrical point of view a family of 60 insulin homologous sequences ranging on a large variety of living organisms from human to the nematode C. elegans. We show that the distances between sequences provide important information about the evolution and function of insulin.

	%P 1731 - 1740