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The Development of New Technologies for Medicine and Agroecology by Using Spherosomes
Abstract:Article devoted to the development of technologies for medicine and agroecology by using plant organelle – spherosome. Technological method of purification and isolation of this organelle by using novel nanostructured carbon sorbent – “nanocarbosorb" ARK type are presented. Also the methods of preparation of nanocontainers based on using of spherosome with loaded isosorbide dinitrate, piroxicam or diclofenak are exhibited. We found that the spherosome could be applied for ecological aims as bioregulator and also as biosensor for determination of ammonia ions in water reservoirs at concentration range 1mM to 100mM.
Digital Object Identifier (DOI): doi.org/10.5281/zenodo.1070869Procedia APA BibTeX Chicago EndNote Harvard JSON MLA RIS XML ISO 690 PDF Downloads 1123
 M. K. Gilmanov, R.Dilbarkanova, Structure and functions of spherosomes of plant cells. Almaty: Gylym, 1997, pp. 52-88. (In russian)
 M. G. Low, "Biochemistry of the glycosyl-phosphatidylinositol membrane protein anchors," Biochemistry Journal, vol. 244, pp. 1-13, 1987.
 Gilmanov M.K., Dilbarcanova R., Sultanbaev B.E. // Method for preparing phosphatidylinositol from vegetable matter // The Commissioner of patents and trademarks. Patent No 4,977,091 USA, December 11, 1990.
 Z.A. Mansurov, "Some Applications of nanocarbon materials for novel devices", Nonoscale-Devices - Fundamentals, Springer, vol. 233, pp. 355-368, 2006.
 J. Folch, M. Lees, G. S. Stanley, "A simple method for isolation and purification of total lipids for animal tissues,". J. Biological Chemistry, vol. 226, pp. 497-509, 1957.
 M. Kates, Technique of lipidology: Analysis, isolation and identification of lipids. American Elsevier Pub.Co., Inc., New York, 1973, pp. 341.
 N.A. Samenov, M.K. Gilmanov, S.M. Gilmanova "Methods of loading of liposomes," Patent of the Republic of Kazakhstan 2004/1191.1, August 17, 2004.
 M.K. Gilmanov, S.M. Gilmanov, S.M. Gilmanova "Rhizoginin-S biostimulator for vegetative plant propagation, micropropagation and the production of regenerates from plant cell and tissue cultures" The international Bureau of WIPO 34, chemin des Colombettes 1211 Geneva 20, Switzerland, WO 02/11541 A1 - PCT/KZ00/00005, February 14, 2002.
 M.M. Senyavin, Determination of normalized components in waste waters, Nauka, Moskva, pp. 132, 1987. (In russian)
 doi:10.1016/j.bios.2008.05.009 M.K. Gilmanov, A.R. Kerimkulova, A.N. Sabitova, S.A. Ibragimova. "The phosphatidylinositol-protein nanocomplex as a new biosensor for ecological monitoring and clinical diagnostic", J. Biosensors and bioelectronics, to be published.