%0 Journal Article
	%A Hendriëtte van der Walt and  Lesley Chown and  Richard Harris and  Ndabenhle Sosibo and  Robert Tshikhudo
	%D 2010
	%J International Journal of Biotechnology and Bioengineering
	%B World Academy of Science, Engineering and Technology
	%I Open Science Index 44, 2010
	%T Fe3O4 and Fe3O4@Au Nanoparticles: Synthesis and Functionalisation for Biomolecular Attachment
	%U https://publications.waset.org/pdf/7836
	%V 44
	%X The use of magnetic and magnetic/gold core/shell
nanoparticles in biotechnology or medicine has shown good promise
due to their hybrid nature which possesses superior magnetic and
optical properties. Some of these potential applications include
hyperthermia treatment, bio-separations, diagnostics, drug delivery
and toxin removal. Synthesis refinement to control geometric and
magnetic/optical properties, and finding functional surfactants for
biomolecular attachment, are requirements to meet application
specifics.
Various high-temperature preparative methods were used for the
synthesis of iron oxide and gold-coated iron oxide nanoparticles.
Different surface functionalities, such as 11-aminoundecanoic and
11-mercaptoundecanoic acid, were introduced on the surface of the
particles to facilitate further attachment of biomolecular functionality
and drug-like molecules. Nanoparticle thermal stability, composition,
state of aggregation, size and morphology were investigated and the
results from techniques such as Fourier Transform-Infra Red
spectroscopy (FT-IR), Ultraviolet visible spectroscopy (UV-vis),
Transmission Electron Microscopy (TEM) and thermal analysis are
discussed.
	%P 560 - 564