@article{(Open Science Index):https://publications.waset.org/pdf/5327, title = {Effect of Plasma Therapy on Epidermal Regeneration}, author = {Magda Bădescu and Daniela Jitaru and C.Grigoraş and L.Bădescu and I. Topala and Manuela Ciocoiu}, country = {}, institution = {}, abstract = {The purpose of our study was to compare spontaneous re-epithelisation characteristics versus assisted re-epithelisation. In order to assess re-epithelisation of the injured skin, we have imagined and designed a burn wound model on Wistar rat skin. Our aim was to create standardised, easy reproducible and quantifiable skin lesions involving entire epidermis and superficial dermis. We then have applied the above mentioned therapeutic strategies to compare regeneration of epidermis and dermis, local and systemic parameter changes in different conditions. We have enhanced the reepithelisation process under a moist atmosphere of a polyurethane wound dress modified with helium non-thermal plasma, and with the aid of direct cold-plasma treatment respectively. We have followed systemic parameters change: hematologic and biochemical parameters, and local features: oxidative stress markers and histology of skin in the above mentioned conditions. Re-epithelisation is just a part of the skin regeneration process, which recruits cellular components, with the aid of epidermal and dermal interaction via signal molecules.}, journal = {International Journal of Biomedical and Biological Engineering}, volume = {6}, number = {4}, year = {2012}, pages = {74 - 79}, ee = {https://publications.waset.org/pdf/5327}, url = {https://publications.waset.org/vol/64}, bibsource = {https://publications.waset.org/}, issn = {eISSN: 1307-6892}, publisher = {World Academy of Science, Engineering and Technology}, index = {Open Science Index 64, 2012}, }