TY - JFULL AU - Sahar Y. Al-Okbi and Doha A. Mohamed and Thanaa E. Hamed and Ahmed Ms Hussein PY - 2013/8/ TI - Cereals' Products with Red Grape and Walnut Extracts as Functional Foods for Prevention of Kidney Dysfunction T2 - International Journal of Nutrition and Food Engineering SP - 583 EP - 590 VL - 7 SN - 1307-6892 UR - https://publications.waset.org/pdf/16335 PU - World Academy of Science, Engineering and Technology NX - Open Science Index 79, 2013 N2 - In the present research, two nutraceuticals made from red grape and walnut that showed previously to improve kidney dysfunction were incorporated separately into functional foods' bread made from barley and rice bran. The functional foods were evaluated in rats in which chronic renal failure was induced through feeding diet rich in adenine and phosphate (APD). The evaluation based on assessing kidney function, oxidative stress, inflammatory biomarkers and body weight gain. Results showed induction of chronic kidney failure reflected in significant increase in plasma urea, creatinine, malondialdehyde, tumor necrosis factor- α and low density lipoprotein cholesterol along with significant reduction of plasma albumin, and total antioxidant and creatinine clearance and body weight gain on feeding APD compared to control healthy group. Feeding the functional foods produced amelioration in the different biochemical parameters and body weight gain indicating improvement in kidney function. ER -