TY - JFULL AU - André M. Ornelas and Lise P. Labéjof and Ligia V. Lage dos Santos and Jackson A. Santos PY - 2012/7/ TI - Assessment of Maternal and Embryo-Fetal Toxicity of Copper Oxide Fungicide T2 - International Journal of Medical and Health Sciences SP - 252 EP - 255 VL - 6 SN - 1307-6892 UR - https://publications.waset.org/pdf/15592 PU - World Academy of Science, Engineering and Technology NX - Open Science Index 66, 2012 N2 - The excessive use of agricultural pesticides and the resulting contamination of food and beds of rivers have been a recurring problem nowadays. Some of these substances can cause changes in endocrine balance and impair reproductive function of human and animal population. In the present study, we evaluated the possible effects of the fungicide cuprous copper oxide Sandoz® on pregnant Wistar rats. They received a daily oral administration of 103 or 3.103 mg/kg of the fungicide from the 6th to the 15th day of gestation. On day 21 of gestation, the maternal and fetal toxicity parameters and indices were determined. The administration of cuprous oxide (Copper Sandoz) in Wistar rats, the period of organogenesis, revealed no evidence of maternal toxicity or embryo at the studied doses. ER -