@article{(Open Science Index):https://publications.waset.org/pdf/15320,
	  title     = {Analysis of Physicochemical Properties on Prediction of R5, X4 and R5X4 HIV-1 Coreceptor Usage},
	  author    = {Kai-Ti Hsu and  Hui-Ling Huang and  Chun-Wei Tung and  Yi-Hsiung Chen and  Shinn-Ying Ho},
	  country	= {},
	  institution	= {},
	  abstract     = {Bioinformatics methods for predicting the T cell
coreceptor usage from the array of membrane protein of HIV-1 are
investigated. In this study, we aim to propose an effective prediction
method for dealing with the three-class classification problem of
CXCR4 (X4), CCR5 (R5) and CCR5/CXCR4 (R5X4). We made
efforts in investigating the coreceptor prediction problem as follows: 1)
proposing a feature set of informative physicochemical properties
which is cooperated with SVM to achieve high prediction test
accuracy of 81.48%, compared with the existing method with
accuracy of 70.00%; 2) establishing a large up-to-date data set by
increasing the size from 159 to 1225 sequences to verify the proposed
prediction method where the mean test accuracy is 88.59%, and 3)
analyzing the set of 14 informative physicochemical properties to
further understand the characteristics of HIV-1coreceptors.},
	    journal   = {International Journal of Biomedical and Biological Engineering},
	  volume    = {3},
	  number    = {5},
	  year      = {2009},
	  pages     = {262 - 269},
	  ee        = {https://publications.waset.org/pdf/15320},
	  url   	= {https://publications.waset.org/vol/29},
	  bibsource = {https://publications.waset.org/},
	  issn  	= {eISSN: 1307-6892},
	  publisher = {World Academy of Science, Engineering and Technology},
	  index 	= {Open Science Index 29, 2009},
	}