%0 Journal Article %A M. Seifi and A. Ghasemi and M. Khosravi and M. Salimi and S. Jahandideh and J. Sherizadeh and F. S. Hashemizadeh and R. Khodaei %D 2009 %J International Journal of Medical and Health Sciences %B World Academy of Science, Engineering and Technology %I Open Science Index 33, 2009 %T Genetic Variants and Atherosclerosis %U https://publications.waset.org/pdf/14682 %V 33 %X Atherosclerosis is the condition in which an artery wall thickens as the result of a build-up of fatty materials such as cholesterol. It is a syndrome affecting arterial blood vessels, a chronic inflammatory response in the walls of arteries, in large part due to the accumulation of macrophage white blood cells and promoted by low density (especially small particle) lipoproteins (plasma proteins that carry cholesterol and triglycerides) without adequate removal of fats and cholesterol from the macrophages by functional high density lipoproteins (HDL). It is commonly referred to as a hardening or furring of the arteries. It is caused by the formation of multiple plaques within the arteries. %P 251 - 259