@article{(Open Science Index):https://publications.waset.org/pdf/13392,
	  title     = {Proteomic Analysis of Tumor Tissue after Treatment with Ascorbic Acid},
	  author    = {Seyeon Park and  Mi Jang},
	  country	= {},
	  institution	= {},
	  abstract     = {Tumor cells have an invasive and metastatic phenotype
that is the main cause of death for cancer patients. Tumor
establishment and penetration consists of a series of complex
processes involving multiple changes in gene expression. In this study,
intraperitoneal administration of a high concentration of ascorbic acid
inhibited tumor establishment and decreased tumor mass in BALB/C
mice implanted with S-180 sarcoma cancer cells. To identify proteins
involved in the ascorbic acid-mediated inhibition of tumor
progression, changes in the tumor proteome associated with ascorbic
acid treatment of BALB/C mice implanted with S-180 were
investigated using two-dimensional gel electrophoresis and mass
spectrometry. Twenty protein spots were identified whose expression
was different between control and ascorbic acid treatment groups.},
	    journal   = {International Journal of Biomedical and Biological Engineering},
	  volume    = {4},
	  number    = {4},
	  year      = {2010},
	  pages     = {157 - 160},
	  ee        = {https://publications.waset.org/pdf/13392},
	  url   	= {https://publications.waset.org/vol/40},
	  bibsource = {https://publications.waset.org/},
	  issn  	= {eISSN: 1307-6892},
	  publisher = {World Academy of Science, Engineering and Technology},
	  index 	= {Open Science Index 40, 2010},
	}