@article{(Open Science Index):https://publications.waset.org/pdf/1316,
	  title     = {Highly Sensitive Label Free Biosensor for Tumor Necrosis Factor},
	  author    = {Tze Sian Pui and  Tushar Bansal and  Patthara Kongsuphol and  Sunil K. Arya},
	  country	= {},
	  institution	= {},
	  abstract     = {We present a label-free biosensor based on
electrochemical impedance spectroscopy for the detection of proinflammatory
cytokine Tumor Necrosis Factor (TNF-α). Secretion of
TNF-α has been correlated to the onset of various diseases including
rheumatoid arthritis, Crohn-s disease etc. Gold electrodes were
patterned on a silicon substrate and self assembled monolayer of
dithiobis-succinimidyl propionate was used to develop the biosensor
which achieved a detection limit of ~57fM. A linear relationship was
also observed between increasing TNF-α concentrations and chargetransfer
resistance within a dynamic range of 1pg/ml – 1ng/ml.},
	    journal   = {International Journal of Biomedical and Biological Engineering},
	  volume    = {6},
	  number    = {9},
	  year      = {2012},
	  pages     = {443 - 446},
	  ee        = {https://publications.waset.org/pdf/1316},
	  url   	= {https://publications.waset.org/vol/69},
	  bibsource = {https://publications.waset.org/},
	  issn  	= {eISSN: 1307-6892},
	  publisher = {World Academy of Science, Engineering and Technology},
	  index 	= {Open Science Index 69, 2012},
	}