@article{(Open Science Index):https://publications.waset.org/pdf/12487, title = {Stereoselective Reduction of Amino Ketone with Sodium Borohydride in the Presence of Metal Chloride. A Simple Pathway to S-Propranolol}, author = {R. Inkum and A. Teerawutgulrag and P. Puangsombat and N. Rakariyatham}, country = {}, institution = {}, abstract = {Propranolol is worldwide hypertension drug that is active in S-isomer. Patients must use this drug throughout their lives, and this action employsa significant level of expenditure. A simpler synthesis and lower cost can reduce the price for the patient. A sis pathway of S-propranolol starting from protection of (R,S)-propranolol with di-t-butyldicarbonate and then the product is oxidized with pyridiniumchlorochromate. The selective reduction of ketone occurrs with sodiumborohydride in the presence of metal chloride provided S-propranolol. }, journal = {International Journal of Chemical and Molecular Engineering}, volume = {6}, number = {7}, year = {2012}, pages = {637 - 640}, ee = {https://publications.waset.org/pdf/12487}, url = {https://publications.waset.org/vol/67}, bibsource = {https://publications.waset.org/}, issn = {eISSN: 1307-6892}, publisher = {World Academy of Science, Engineering and Technology}, index = {Open Science Index 67, 2012}, }