@article{(Open Science Index):https://publications.waset.org/pdf/1161, title = {Unnoticeable Mumps Infection in India: Does MMR Vaccine Protect against Circulating Mumps Virus Genotype C?}, author = {Jeevan Malayan and Aparna Warrier and Padmasani Venkat Ramanan and Sanjeeva Reddy N and Elanchezhiyan Manickan}, country = {}, institution = {}, abstract = {MMR vaccine failure had been reported globally and here we report that it occurs now in India. Samples were collected from clinically suspected mumps cases were subjected for anti mumps antibodies, virus isolation, RT-PCR, sequencing and phylogenetic tree analysis. 56 samples collected from men and women belonging to various age groups. 30 had been vaccinated and the status of 26 patients was unknown. 28 out of 30 samples were found to be symptomatic and positive for Mumps IgM, indicating active mumps infection in 93.4% of the vaccinated population. A phylogenetic tree comparison of the clinical isolate is shown to be genotype C which is distinct from vaccine strain. Our study clearly sending warning signs that MMR vaccine is a failure and it needs to be revamped for the human use by increasing its efficacy and efficiency.}, journal = {International Journal of Biotechnology and Bioengineering}, volume = {6}, number = {11}, year = {2012}, pages = {1011 - 1017}, ee = {https://publications.waset.org/pdf/1161}, url = {https://publications.waset.org/vol/71}, bibsource = {https://publications.waset.org/}, issn = {eISSN: 1307-6892}, publisher = {World Academy of Science, Engineering and Technology}, index = {Open Science Index 71, 2012}, }