Weronika Kurowska-Nouyrigat and Jacek Szumbarski
Numerical Simulation of Restenosis in a Stented Coronary Artery
268 - 272
2009
3
10
International Journal of Medical and Health Sciences
https://publications.waset.org/pdf/10419
https://publications.waset.org/vol/34
World Academy of Science, Engineering and Technology
Nowadays, cardiac disease is one of the most common
cause of death. Each year almost one million of angioplasty interventions and stents implantations are made all over the world.
Unfortunately, in 2030 of cases neointimal proliferations leads to
restenosis occurring within the following period of 36 months. Three major factors are believed to contribute mostly to the edge
restenosis (a) mechanical damage of the arterys wall caused by the
stent implantation, (b) interaction between the stent and the blood constituents and (c) endothelial growth stimulation by small (lower
that 1.5 Pa) and oscillating wall shear stress. Assuming that this last actor is particularly important, a numerical model of restenosis
basing on wall shear stress distribution in the stented artery was elaborated. A numerical simulations of the development of instent
restenosis have been performed and realistic geometric patterns of a
progressing lumen reduction have been obtained
Open Science Index 34, 2009