WASET
	%0 Journal Article
	%A Rameswar Debnath and  Haruhisa Takahashi
	%D 2010
	%J International Journal of Bioengineering and Life Sciences
	%B World Academy of Science, Engineering and Technology
	%I Open Science Index 46, 2010
	%T A Comparison of SVM-based Criteria in Evolutionary Method for Gene Selection and Classification of Microarray Data
	%U https://publications.waset.org/pdf/10270
	%V 46
	%X An evolutionary method whose selection and recombination
operations are based on generalization error-bounds of
support vector machine (SVM) can select a subset of potentially
informative genes for SVM classifier very efficiently [7]. In this
paper, we will use the derivative of error-bound (first-order criteria)
to select and recombine gene features in the evolutionary process,
and compare the performance of the derivative of error-bound with
the error-bound itself (zero-order) in the evolutionary process. We
also investigate several error-bounds and their derivatives to compare
the performance, and find the best criteria for gene selection
and classification. We use 7 cancer-related human gene expression
datasets to evaluate the performance of the zero-order and first-order
criteria of error-bounds. Though both criteria have the same strategy
in theoretically, experimental results demonstrate the best criterion
for microarray gene expression data.
	%P 737 - 741