Vahid Nademi
Improved Blood GlucoseInsulin Monitoring with DualLayer Predictive Control Design
398 - 402
2018
12
9
International Journal of Biomedical and Biological Engineering
https://publications.waset.org/pdf/10009549
https://publications.waset.org/vol/141
World Academy of Science, Engineering and Technology
In response to widely used wearable medical devices equipped with a continuous glucose monitor (CGM) and insulin pump, the advanced control methods are still demanding to get the full benefit of these devices. Unlike costly clinical trials, implementing effective insulinglucose control strategies can provide significant contributions to the patients suffering from chronic diseases such as diabetes. This study deals with a key role of twolayer insulinglucose regulator based on modelpredictivecontrol (MPC) scheme so that the patient’s predicted glucose profile is in compliance with the insulin level injected through insulin pump automatically. It is achieved by iterative optimization algorithm which is called an integrated perturbation analysis and sequential quadratic programming (IPASQP) solver for handling uncertainties due to unexpected variations in glucoseinsulin values and body’s characteristics. The feasibility evaluation of the discussed control approach is also studied by means of numerical simulations of two case scenarios via measured data. The obtained results are presented to verify the superior and reliable performance of the proposed control scheme with no negative impact on patient safety.
Open Science Index 141, 2018