Sanjaykumar R. Patel and Parth R. Kayastha
Ultrasound Assisted Cooling Crystallization of Lactose Monohydrate
58 - 61
2018
12
2
International Journal of Chemical and Molecular Engineering
https://publications.waset.org/pdf/10008532
https://publications.waset.org/vol/134
World Academy of Science, Engineering and Technology
αlactose monohydrate is widely used in the pharmaceutical industries as an inactive substance that acts as a vehicle or a medium for a drug or other active substance. It is a byproduct of dairy industries, and the recovery of lactose from whey not only boosts the improvement of the economics of whey utilization but also causes a reduction in pollution as lactose recovery can reduce the BOD of whey by more than 80. In the present study, levels of process parameters were kept as initial lactose concentration (3050 ww), sonication amplitude (2040), sonication time (26 hours), and crystallization temperature (1020 oC) for the recovery of lactose in ultrasound assisted cooling crystallization. In comparison with cooling crystallization, the use of ultrasound enhanced the lactose recovery by 39.17 (ww). The parameters were optimized for the lactose recovery using Taguchi Method. The optimum conditions found were initial lactose concentration at level 3 (50 ww), amplitude of sonication at level 2 (40), the sonication time at level 3 (6 hours), and crystallization temperature at level 1 (10 °C). The maximum recovery was found to be 85.85 at the optimum conditions. Sonication time and the initial lactose concentration were found to be significant parameters for the lactose recovery.
Open Science Index 134, 2018