%0 Journal Article
	%A Yogesh D. Bansod and  Jiri Bursa
	%D 2015
	%J International Journal of Bioengineering and Life Sciences
	%B World Academy of Science, Engineering and Technology
	%I Open Science Index 105, 2015
	%T Continuum-Based Modelling Approaches for Cell Mechanics
	%U https://publications.waset.org/pdf/10002070
	%V 105
	%X The quantitative study of cell mechanics is of
paramount interest, since it regulates the behaviour of the living cells
in response to the myriad of extracellular and intracellular
mechanical stimuli. The novel experimental techniques together with
robust computational approaches have given rise to new theories and
models, which describe cell mechanics as combination of
biomechanical and biochemical processes. This review paper
encapsulates the existing continuum-based computational approaches
that have been developed for interpreting the mechanical responses of
living cells under different loading and boundary conditions. The
salient features and drawbacks of each model are discussed from both
structural and biological points of view. This discussion can
contribute to the development of even more precise and realistic
computational models of cell mechanics based on continuum
approaches or on their combination with microstructural approaches,
which in turn may provide a better understanding of
mechanotransduction in living cells.
	%P 969 - 980