S. S. Pati and L. Herojit Singh and A. C. Oliveira and V. K. Garg
Chitosan Functionalized Fe3O4Au CoreShell Nanomaterials for Targeted Drug Delivery
670 - 673
2015
9
6
International Journal of Pharmacological and Pharmaceutical Sciences
https://publications.waset.org/pdf/10001554
https://publications.waset.org/vol/102
World Academy of Science, Engineering and Technology
Chitosan functionalized Fe3O4Au core shell
nanoparticles have been prepared using a twostep wet chemical
approach using NaBH4 as reducing agent for formation of Au in
ethylene glycol. Xray diffraction studies shows individual phases of
Fe3O4 and Au in the as prepared samples with crystallite size of 5.9
and 11.4 nm respectively. The functionalization of the coreshell
nanostructure with Chitosan has been confirmed using Fourier
transform infrared spectroscopy along with signatures of octahedral
and tetrahedral sites of Fe3O4 below 600cm1. Mössbauer
spectroscopy shows decrease in particleparticle interaction in
presence of Au shell (72 sextet) than pure oleic coated Fe3O4
nanoparticles (88 sextet) at room temperature. At 80K, oleic acid
coated Fe3O4 shows only sextets whereas the Chitosan functionalized
Fe3O4 and Chitosan functionalized Fe3O4Au core shell show
presence of 5 and 11 doublet, respectively.
Open Science Index 102, 2015