@article{(Open Science Index):https://publications.waset.org/pdf/10001554, title = {Chitosan Functionalized Fe3O4@Au Core-Shell Nanomaterials for Targeted Drug Delivery}, author = {S. S. Pati and L. Herojit Singh and A. C. Oliveira and V. K. Garg}, country = {}, institution = {}, abstract = {Chitosan functionalized Fe3O4-Au core shell nanoparticles have been prepared using a two-step wet chemical approach using NaBH4 as reducing agent for formation of Au in ethylene glycol. X-ray diffraction studies shows individual phases of Fe3O4 and Au in the as prepared samples with crystallite size of 5.9 and 11.4 nm respectively. The functionalization of the core-shell nanostructure with Chitosan has been confirmed using Fourier transform infrared spectroscopy along with signatures of octahedral and tetrahedral sites of Fe3O4 below 600cm-1. Mössbauer spectroscopy shows decrease in particle-particle interaction in presence of Au shell (72% sextet) than pure oleic coated Fe3O4 nanoparticles (88% sextet) at room temperature. At 80K, oleic acid coated Fe3O4 shows only sextets whereas the Chitosan functionalized Fe3O4 and Chitosan functionalized Fe3O4@Au core shell show presence of 5 and 11% doublet, respectively.}, journal = {International Journal of Pharmacological and Pharmaceutical Sciences}, volume = {9}, number = {6}, year = {2015}, pages = {670 - 673}, ee = {https://publications.waset.org/pdf/10001554}, url = {https://publications.waset.org/vol/102}, bibsource = {https://publications.waset.org/}, issn = {eISSN: 1307-6892}, publisher = {World Academy of Science, Engineering and Technology}, index = {Open Science Index 102, 2015}, }