%0 Journal Article
	%A Yazhi Huang and  Jing Yang and  Dingge Ying and  Yan Zhang and  Vorasuk Shotelersuk and  Nattiya Hirankarn and  Pak Chung Sham and  Yu Lung Lau and  Wanling Yang
	%D 2015
	%J International Journal of Bioengineering and Life Sciences
	%B World Academy of Science, Engineering and Technology
	%I Open Science Index 99, 2015
	%T Accurate HLA Typing at High-Digit Resolution from NGS Data
	%U https://publications.waset.org/pdf/10000791
	%V 99
	%X Human leukocyte antigen (HLA) typing from next
generation sequencing (NGS) data has the potential for applications in
clinical laboratories and population genetic studies. Here we introduce
a novel technique for HLA typing from NGS data based on
read-mapping using a comprehensive reference panel containing all
known HLA alleles and de novo assembly of the gene-specific short
reads. An accurate HLA typing at high-digit resolution was achieved
when it was tested on publicly available NGS data, outperforming
other newly-developed tools such as HLAminer and PHLAT.

	%P 263 - 271